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4.93/5 based on 801 review

Age Defying Lift & Firm Cream

$39.99
Triple King Peptide Complex: Only DERMXELL combines Progeline™, Matrixyl 3000®, and Argireline®—a breakthrough trio you won't find in ordinary creams.
Visibly reduce the look of deep wrinkles for younger-looking skin
💪 Instantly Lift, sculpt & firm sagging face and neck
🌟 Diminish dark spots for a flawless, radiant complexion
💧 Plump, hydrate, and revive skin with 24-hour dewy moisture
🛡️ Soothe, calm, and protect even the most sensitive skin
🏆 Clinically proven: 98% of users saw firmer skin
👩 Formulated in the USA by leading dermatologists
💸 60-day money-back guarantee
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↩️ 60-Day Returns
38,000+ Happy Customers
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DermXell⁺ features a unique blend of advanced peptides—Progeline™, Matrixyl 3000®, and Argireline®—designed to visibly smooth, lift, and tighten your skin without the need for needles or surgery. Simply massage a small amount onto your face and neck each morning and night.

With consistent use, you can enjoy firmer, more radiant skin and a rejuvenated appearance. In clinical studies, 98% of users noticed firmer, more youthful-looking skin with regular use.

Dermxell's Golden 4-D Youth Ritual unlocks four cascading benefits in a single, luxurious cream.

1. Drench – It instantly floods your complexion with five weights of hyaluronic acid, delivering deep, thirst-quenching hydration from the very first touch.

2. Dewify – Within just three days, the Tri-Peptide Lifting Complex™ coaxes out a glass-skin "honeymoon glow," so you wake up visibly more radiant.

3. Diminish – Clinically proven peptides (Progeline™, Matrixyl 3000®, Argireline®) go to work beneath the surface, softening wrinkles and lifting sagging contours as they rebuild dermal density.

4. Defend – A ceramide-antioxidant shield then locks everything in, fortifying your barrier against pollution, blue light, and daily stressors—so today's glow becomes tomorrow's norm.

Absolutely. DermXell⁺ is dermatologist-tested, fragrance-free, and 100% paraben-free, so it's safe and gentle for even the most sensitive skin.

Our formula works beautifully on normal, oily, dry, combination, and mature skin—no stinging, redness, or irritation.

Yes! DermXell⁺ is formulated by top dermatologists, clinically tested, and trusted by real women.

Backed by science and recommended by skin experts, you get proven results—without risky or harsh treatments.

Feel smoother, hydrated skin within minutes—see visibly firmer, lifted, younger-looking skin in just 7 days.

For dramatic, lasting results, use DermXell⁺ morning and night for 14 days or more.

Most brands use just one hero peptide—DermXell⁺ delivers three of the world's most advanced, clinically proven king peptides for visibly firmer, smoother, younger-looking skin you can see and feel. No needles, no fillers—just the gold-standard technology dermatologists trust and a clinical trio you won't find in ordinary creams.

✨ Progeline™ - The revolutionary peptide that targets the "aging protein" (progerin) to visibly tighten, lift, and restore skin's youthful density.
✨ Matrixyl 3000® - Clinically proven to supercharge collagen production, plumping and fortifying thin, aging skin.
💉 Argireline® - The famous "needle-free Botox"—relaxes expression lines for instantly smoother skin.
💧 Hyaluronic Acid & Glycerin - Deliver intense, 24-hour hydration for a plumper, glass-skin glow.
🛡️ Multi-Ceramide Complex - Rebuilds your skin's protective barrier for long-lasting resilience.
🌱 Jojoba & Sweet Almond Oils - Nourish, replenish, and balance—leaving skin silky, never shiny.

Zero parabens. Zero fragrance. Zero cruelty. Only science-powered, skin-loving results.

Yes—DermXell⁺ is proudly cruelty-free, never tested on animals, and made with ethically sourced, plant-powered ingredients.

60-Day Satisfaction Guarantee: If the product doesn't meet your expectations, email us within 60 days of delivery to arrange a return and refund.

Get Up To 50% OFF Now

38,000+ Satisfied Customers: Discover the Remarkable Results of DERMXELL⁺ !

I’ve struggled with acne for years, with constant redness and irritation. DERMXELL⁺

has made a real difference—within days, the itching stopped, and after a week, my acne started to clear up. The non-greasy texture absorbs quickly and leaves my skin smoother, with fewer breakouts. It’s gentle and effective for my sensitive skin.

Nicole R. 

In my late 30s, I started dealing with rosacea, fine lines, and dark spots. After just a week of using DERMXELL⁺, my skin feels calmer, the redness has reduced, and my fine lines are softer. My dark spots are fading, and my skin looks smoother. It absorbs quickly and isn’t greasy—definitely my go-to now.

Carolyn J. 

I’m usually pretty skeptical, but after hearing my friend rave about DERMXELL⁺, I decided to give it a try. Two weeks in, and my skin feels plumper, especially on my cheeks and neck. My deep wrinkles have definitely improved. I’ll update if the results last, but so far, I’m really impressed.

Marianne N.

8 Proven Benefits for Ageless, Firm, and Radiant Skin—Experience the DERMXELL⁺ Difference

Powered by our breakthrough Triple King Peptide Complex, DERMXELL⁺ delivers eight visible results—from age-defying lift to deep, lasting hydration.

Age-Defying

Reverse the visible signs of aging and unveil timeless, youthful skin.

Clarifying & Brightening

Fading dark spots and uneven skin tone for a clearer, more luminous skin.

Sculpting

Visibly lift and sculpt your skin for a firmer, more youthful appearance.

Deep Hydration

Nourish and deeply hydrate for plumper, softer skin that glows with health.

Revitalizing

Restore your skin’s strength and elasticity for a smooth, firm texture.

Elasticity & Contour Renewal

Enhance your natural contours and redefine your jawline and neck.

Tightening & Firming

Tighten and firm skin for a smooth, tightened appearance, reducing fine lines and sagging.

Skin Barrier Defense

Strengthen and protect your skin’s natural barrier to lock in hydration and shield against daily environmental stressors.

How to Use DERMXELL⁺ for Best Results

STEP 1: Start with Clean, Dry Skin

Cleanse your face and neck thoroughly, then gently pat dry. This ensures maximum absorption of our clinical actives.


STEP 2: Apply a Quarter-Size Amount

Dispense a small amount of DermXell⁺ Age-Defying Lift & Firm Cream. Using your fingertips, dot onto your cheeks, forehead, chin, neck, and jawline.


STEP 3: Massage in Upward Motions

Gently massage the cream into your skin using upward, sweeping strokes—especially along the jawline, neck, and areas prone to sagging or fine lines.


STEP 4: Allow Full Absorption (3–5 Minutes)

Wait a few minutes before layering other products or makeup. DermXell⁺’s lightweight texture absorbs quickly, leaving no residue.


STEP 5: Use Twice Daily

For maximum age-defying benefits, apply DermXell⁺ morning and night as the last step of your skincare routine.

The Only Cream Fused with 3 King Peptides and Next-Gen Ceramides

Progeline™ – Advanced Pro-Aging Peptide

A cutting-edge biomimetic peptide clinically shown to inhibit progerin, the “aging protein” that causes skin to lose firmness with age. Progeline™ supports skin’s structure for visibly firmer contours, reduced sagging, and a smoother, more lifted appearance—often seen in as little as 7 days.

Matrixyl 3000® – Collagen-Boosting Peptide Complex

This clinically proven peptide duo (palmitoyl tripeptide-1 & tetrapeptide-7) triggers the skin’s natural collagen production to restore youthful thickness and elasticity. Matrixyl 3000® has been shown in clinical studies to reduce wrinkle depth, improve skin texture, and visibly rejuvenate thinning or aging skin.

Argireline® – Line-Relaxing Peptide (“Needle-Free Botox”)

A patented hexapeptide that safely targets the facial muscles responsible for expression lines and wrinkles—without injections. Argireline® works by reducing repetitive muscle contractions, delivering a visibly smoother, softer, more youthful appearance—ideal for crow’s feet, frown lines, and forehead creases.

Multi-Ceramide Complex (Ceramide NP, AP, EOP) – Barrier Restoring Lipids

A dermatologist-preferred blend of three essential ceramides that naturally occur in healthy, youthful skin. This complex rebuilds and fortifies the skin’s protective barrier, locking in moisture, boosting resilience, and defending against dryness, sensitivity, and environmental stress.

Hyaluronic Acid – Deep Hydration Molecule

A superstar molecule that holds up to 1,000 times its weight in water. Hyaluronic Acid penetrates deeply and delivers 24-hour hydration for plumper, dewier skin, reducing the look of fine lines and creating a smooth, cushiony feel.

Oligopeptides & Tetrapeptides – Next Generation Lifting Actives

Advanced peptide technology—including palmitoyl tripeptide-5 and acetyl hexapeptide-8—signals skin to repair, lift, and contour from within. These actives work synergistically to support firmness, visibly sculpt jawline and cheeks, and deliver a noticeable anti-aging effect over time.

Dermatologist’s Intensive Tips

• Apply After Serum: For extra lifting power, use DermXell⁺ after your favorite serum and before sunscreen (AM) or night cream (PM).

• Twice Daily for Best Results: Consistent morning and evening use delivers visibly firmer, smoother, more radiant skin—most users see improvement in just 7–21 days.

• Safe for All Skin Types: Dermatologist-tested for sensitive, dry, combination, or mature skin.


For Deep Wrinkles & Stubborn Areas

• For deeper wrinkles or advanced sagging, apply a generous layer of DermXell⁺ to the problem area.

• Cover with a clean, soft wrap (such as facial cotton or a silicone mask) and leave on for 10–15 minutes for an intensive boost.

• Remove the wrap, then gently massage any remaining cream in circular motions to encourage full absorption and maximize firming and smoothing benefits.


For best results, repeat this intensive treatment 2–3 times per week alongside your daily routine.

Clinically monitored study & real-user results

Pure by Choice. Proven by Science. Safe for All.

DERMXELL+ Product Features
Paraben Free Fragrance Free Cruelty Free BHA Free Sulfate Free Phthalate Free

Why Choose DERMXELL⁺ Over Ordinary Creams?

Why Choose DERMXELL⁺ Over Ordinary Creams?

The Only All-in-One Cream with 3 King Peptides—See a Transformation in Just 7 Days

The Only All-in-One Cream with 3 King Peptides—See a Transformation in Just 7 Days

Frequently Asked Questions

DERMXELL FAQ
Many users notice improved hydration and a healthy, radiant glow soon after starting Dermxell, thanks to the benefits of hyaluronic acid in our formula. In a dermatologist-supervised clinical study, 98% of participants reported softer and smoother-feeling skin with regular daily use.

Instrumental testing also confirmed measurable improvements in skin firmness and elasticity. Dermxell is formulated to be gentle and suitable for sensitive skin—over 99% of users experienced no irritation during the trial.

As with any skincare product, individual results may vary. For best results, use Dermxell twice daily as directed. Every purchase is protected by our 60-day money-back guarantee, so you can try Dermxell risk-free.
Yes. The formula was developed to address modern "tech-neck" lines as well as classic "turkey-neck" laxity. Clinical users applying twice daily reported visibly smoother horizontal bands and a more defined jaw contour within 4–6 weeks, thanks to collagen-supporting tetrapeptides and barrier-strengthening niacinamide.
Yes. Dermxell™ has been shown in clinical evaluations to reduce visible hyperpigmentation and promote a more uniform complexion within 4–6 weeks of twice-daily use, thanks to its peptide-driven cell-renewal system, barrier-strengthening ceramide complex, and antioxidant vitamin E that limits new pigment formation.
Absolutely. It is dermatologist-tested, fragrance-free, hypoallergenic and non-comedogenic. Retinol is encapsulated for slow release, so you gain anti-ageing benefits without the stinging or redness many sensitive-skin users fear. If your skin is highly reactive, start with evening use for the first week, then increase as tolerated.
Absolutely. Think of this cream as your moisturizing-treatment step—it layers seamlessly with the products you already use.

Morning: cleanse → antioxidant or hydrating serum → this cream → broad-spectrum SPF → makeup. Its fast-absorbing texture prevents pilling, so foundation glides on smoothly.

Evening: cleanse → prescription retinoid or exfoliating acid (if you use one) → this cream. It calms potential irritation and seals in moisture overnight. A pea-size amount is sufficient for face, neck, and chest. Allow about one minute for it to settle before applying sunscreen or makeup.
Yes. Dermxell™ has a lightweight, fast-absorbing cream texture that settles in under one minute, leaving a smooth, satin finish—no sticky residue, no shine, and no "pilling" when foundation or sunscreen is applied. Even in humid climates, users describe the feel as breathable and comfortably non-greasy.
With twice-daily use, a 50 ml jar lasts about 2-3 weeks. Most customers choose the 3-Pack, which covers a full 6-9-week protocol, saves 25%—enough time to see peak collagen and firmness results.
Orders ship within 24 hours. Estimated transit windows are 7–10 business days for the U.S., 7–14 days for Canada/UK, and 7–12 days to most other destinations. Actual delivery times may vary by carrier and location. A tracking link is emailed the moment your parcel is scanned.
Payments are protected by 256-bit SSL encryption and PCI Level 1 processing—the same security your bank uses. U.S. and most EU orders ship below de minimis thresholds, so no additional duties apply; for other regions, any taxes are calculated upfront to avoid surprises.

REAL CUSTOMERS. REAL REVIEWS. REAL RESULTS.

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Disclaimer: The information provided on this website is for general informational purposes only and should not be interpreted as medical advice. DERMXELL⁺ products have not been evaluated by the U.S. Food and Drug Administration (FDA) and are not intended to diagnose, treat, cure, or prevent any disease or medical condition. For any health concerns, please consult a qualified healthcare professional. For further details, please refer to our Marketing Disclaimer.

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Disclaimer: The information provided on this website is for general informational purposes only and should not be interpreted as medical advice. DERMXELL⁺ products have not been evaluated by the U.S. Food and Drug Administration (FDA) and are not intended to diagnose, treat, cure, or prevent any disease or medical condition. For any health concerns, please consult a qualified healthcare professional. For further details, please refer to our Marketing Disclaimer.

Disclaimer: The information provided on this site is for general informational purposes only and should not be considered medical advice. DermXell⁺ products are not evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare professional regarding any medical concerns or conditions.

Disclaimer: The information provided on this site is for general informational purposes only and should not be considered medical advice. DermXell⁺ products are not evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare professional regarding any medical concerns or conditions.

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DERMXELL⁺ Age Defying Lift & Firm Cream

Try It Now & Save 50% OFF

Try It Now & Save 50% OFF